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    Rabbit Anti-TBX22/Cy7 Conjugated antibody (bs-24075R-Cy7)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-24075R-Cy7
    英文名稱(chēng) Rabbit Anti-TBX22/Cy7 Conjugated antibody
    中文名稱(chēng) Cy7標記的TBX22蛋白抗體
    別    名 ABERS; CLPA; CPX; D230020M15Rik; dJ795G23.1; T box 22; T box protein 22; T box transcription factor TBX22; T-box protein 22; T-box transcription factor TBX22; Tbx22; TBX22_MOUSE; TBXX.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 發(fā)育生物學(xué)  轉錄調節因子  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse, 
    產(chǎn)品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 58kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse TBX22
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    Function:
    Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Seems to be expressed at a low level.

    DISEASE:
    The disease is caused by mutations affecting the gene represented in this entry. Disease description:A congenital mouth abnormality characterized by fissure of the soft and/or hard palate, due to faulty fusion. Some patients also manifest ankyloglossia, a condition in which movements of the tongue are restricted. Complete ankyloglossia is due to fusion between the tongue and the floor of the mouth. Partial ankyloglossia is due to a short lingual frenum or one which is attached too near the tip of the tongue.

    Similarity:
    Contains 1 T-box DNA-binding domain.

    Database links:

    Entrez Gene: 50945 Human

    Entrez Gene: 245572 Mouse

    Entrez Gene: 302369 Rat

    Omim: 300307 Human

    SwissProt: Q9Y458 Human

    SwissProt: Q8K402 Mouse

    Unigene: 374253 Human

    Unigene: 137011 Mouse

    Unigene: 109981 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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