產(chǎn)品編號 | bs-12805R-Gold |
英文名稱(chēng) | Rabbit Anti-STOX1/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標記的STOX1蛋白抗體 |
別 名 | C10orf24; chromosome 10 open reading frame 241; PEE4; storkhead box 1; Storkhead-box protein 1; STOX1; STOX1_HUMAN; Winged-helix domain-containing protein. |
規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細胞生物 發(fā)育生物學(xué) 轉錄調節因子 表觀(guān)遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應 | Human, (predicted: Mouse, Pig, Cow, ) |
產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 111kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human STOX1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Subcellular Location: Nucleus; Nucleus > nucleolus and Cytoplasm. Nucleus. Either found in the cytoplasm or in the nucleus. Nuclear expression of isoform A seems to be restricted to polyploid trophoblast cells. DISEASE: Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]; also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta. Database links: Entrez Gene: 219736 Human Omim: 609397 Human SwissProt: Q6ZVD7 Human Unigene: 37636 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |