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    Rabbit Anti-SLC47A1/APC Conjugated antibody (bs-9284R-APC)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-9284R-APC
    英文名稱(chēng) Rabbit Anti-SLC47A1/APC Conjugated antibody
    中文名稱(chēng) APC標記的溶質(zhì)載體蛋白家族47成員A1抗體
    別    名 1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  細胞生物  信號轉導  細胞膜蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse, Rat,  (predicted: Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 58kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SLC47A1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

    Function:
    Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

    Subcellular Location:
    Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

    Tissue Specificity:
    Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

    Similarity:
    Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

    Database links:

    Entrez Gene: 55244 Human

    Omim: 609832 Human

    SwissProt: Q96FL8 Human

    Unigene: 232054 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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