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    Rabbit Anti-SLC19A1/Cy5 Conjugated antibody (bs-19802R-Cy5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-19802R-Cy5
    英文名稱(chēng) Rabbit Anti-SLC19A1/Cy5 Conjugated antibody
    中文名稱(chēng) Cy5標記的溶質(zhì)載體家族蛋白19成員A1抗體
    別    名 CHMD; FLOT 1; FLOT1; Folate transporter 1; FOLT; IFC 1; IFC-1; IFC1; Intestinal folate carrier 1; Intestinal folate carrier; OTTHUMP00000115459; OTTHUMP00000115460; Placental folate transporter; Reduced folate carrier; Reduced folate carrier protein; REFC; RFC 1; RFC; RFC1; S19A1_HUMAN; SLC19A1; Solute carrier family 19 member 1.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  細胞生物  信號轉導  轉運蛋白  細胞膜蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 64kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SLC19A1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC19A1 include placental choriocarcinoma and thiamine-responsive megaloblastic anemia syndrome. Among its related pathways are Cell Cycle, Mitotic and Metabolism. GO annotations related to this gene include oxidoreductase activity and folic acid transporter activity. An important paralog of this gene is SLC19A2.

    Function:
    Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Placenta, liver, and to a much smaller extent, in lung.

    Post-translational modifications:
    Heavily glycosylated.

    Similarity:
    Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

    Database links:

    Entrez Gene: 6573 Human

    Entrez Gene: 29723 Rat

    Omim: 600424 Human

    SwissProt: P41440 Human

    SwissProt: Q62866 Rat

    Unigene: 84190 Human

    Unigene: 9042 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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