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    Rabbit Anti-SLC34A1/APC Conjugated antibody (bs-19812R-APC)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-19812R-APC
    英文名稱(chēng) Rabbit Anti-SLC34A1/APC Conjugated antibody
    中文名稱(chēng) APC標記的溶質(zhì)載體家族蛋白34成員A1抗體
    別    名 FRTS2; Na(+)-dependent phosphate cotransporter 2A; Na(+)/Pi cotransporter 2A; Na+-phosphate cotransporter type II; naPi-2a; NAPI-3; naPi2a; NAPI3; NPHLOP1; NPT2; NPTIIa; renal sodium-dependent phosphate transporter; renal sodium/phosphate transporter protein 2; SLC11; SLC17A2; SLC17A2, formerly; NPT2A_HUMAN; sodium-dependent phosphate transport protein 2A; sodium-phosphate transport protein 2A; sodium/phosphate co-transporter; sodium/phosphate cotransporter 2A; sodium/phosphate transporter 2, kidney; solute carrier family 17 (sodium phosphate), member 2; solute carrier family 17, member 2, formerly; solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate.   
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  信號轉導  轉運蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Pig, Rabbit, Sheep, Cat, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 69kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SLC34A1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]

    Function:
    May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.

    Subunit:
    Interacts via its C-terminal region with PDZK2 (By similarity). Interacts with SLC9A3R1.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Kidney and lung.

    DISEASE:
    The disease is caused by mutations affecting the gene represented in this entry. Disease description:A disease characterized by decreased renal phosphate absorption, renal phosphate wasting, hypophosphatemia, hyperphosphaturia, hypercalciuria, nephrolithiasis and osteoporosis.

    Similarity:
    Belongs to the SLC34A transporter family.

    Database links:

    Entrez Gene: 282483 Cow

    Entrez Gene: 100735387 Guinea pig

    Entrez Gene: 100058397 Horse

    Entrez Gene: 6569 Human

    Entrez Gene: 20505 Mouse

    Entrez Gene: 100155735 Pig

    Entrez Gene: 733703 Pig

    Entrez Gene: 100009392 Rabbit

    Entrez Gene: 25548 Rat

    Entrez Gene: 443505 Sheep

    Omim: 182309 Human

    SwissProt: Q06495 Human

    SwissProt: Q60825 Mouse

    SwissProt: Q28620 Rabbit

    SwissProt: Q06496 Rat

    SwissProt: O97704 Sheep

    Unigene: 936 Human

    Unigene: 276355 Mouse

    Unigene: 92022 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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