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    Rabbit Anti-SEC61A/Biotin Conjugated antibody (bs-19618R-Bio)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-19618R-Bio
    英文名稱(chēng) Rabbit Anti-SEC61A/Biotin Conjugated antibody
    中文名稱(chēng) 生物素標記的轉運蛋白SEC61A抗體
    別    名 chunp6898; fb62c11; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 1; S61A1_HUMAN; SEC 61; SEC 61A; Sec61 alpha 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha-1; SEC61; Sec61 homolog; SEC61A1; sec61aa.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  信號轉導  轉運蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Dog, Cow, )
    產(chǎn)品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 52kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SEC61A
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

    Function:
    Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

    Subunit:
    Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

    Subcellular Location:
    Endoplasmic reticulum membrane.

    Similarity:
    Belongs to the secY/SEC61-alpha family.

    Database links:

    Entrez Gene: 29927 Human

    Entrez Gene: 505064 Cow

    Entrez Gene: 404006 Dog

    Entrez Gene: 53421 Mouse

    Entrez Gene: 80843 Rat

    Entrez Gene: 192298 Zebrafish

    Omim: 609213 Human

    SwissProt: Q5EA68 Cow

    SwissProt: P38377 Dog

    SwissProt: P61619 Human

    SwissProt: P61620 Mouse

    SwissProt: P61621 Rat

    SwissProt: Q90ZM2 Zebrafish

    Unigene: 518236 Human

    Unigene: 28375 Mouse

    Unigene: 485032 Mouse

    Unigene: 47029 Rat

    Unigene: 51503 Zebrafish



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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