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    Rabbit Anti-HSD17B7/BF647 Conjugated antibody (bs-16528R-BF647)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-16528R-BF647
    英文名稱(chēng) Rabbit Anti-HSD17B7/BF647 Conjugated antibody
    中文名稱(chēng) BF647標記的17β羥類(lèi)固醇脫氫酶7抗體
    別    名 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; 3-keto-steroid reductase; DHB7_HUMAN; Estradiol 17 beta dehydrogenase 7; Estradiol 17-beta-dehydrogenase 7; Hsd17b7; hydroxysteroid (17 beta) dehydrogenase 7; MGC12523; MGC75018; PRAP; SDR37C1; Short chain dehydrogenase/reductase family 37C member 1.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  細胞生物  信號轉導  新陳代謝  細胞膜蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 33kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human HSD17B7
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]

    Function:
    Responsible for the reduction of the keto group on the C-3 of sterols.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.

    Post-translational modifications:
    Phosphorylated.

    Similarity:
    Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

    Database links:

    Entrez Gene: 51478 Human

    Entrez Gene: 15490 Mouse

    Entrez Gene: 29540 Rat

    Omim: 606756 Human

    SwissProt: P56937 Human

    SwissProt: O88736 Mouse

    SwissProt: Q62904 Rat

    Unigene: 492925 Human

    Unigene: 12882 Mouse

    Unigene: 7040 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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