| 產(chǎn)品編號 |
bs-12482R-Cy7 |
| 英文名稱(chēng) |
Rabbit Anti-phospho-APC1 (Ser688)/Cy7 Conjugated antibody
|
| 中文名稱(chēng) |
Cy7標記的磷酸化細胞周期末期促進(jìn)復合蛋白APC1抗體 |
| 別 名 |
phospho-ANAPC1(Ser688); Apc1 (phospho S688); ANAPC 1; ANAPC1; Anaphase promoting complex subunit 1; anaphase-promoting complex 1 (meiotic checkpoint regulator); Anaphase-promoting complex subunit 1; Apc 1; APC1; APC1_HUMAN; Cyclosome subunit 1; MCPR; Meiotic checkpoint regulator; Mitotic checkpoint regulator; Protein Tsg 24; Protein Tsg24; Testis-specific gene 24 protein; TSG 24; TSG24. |
| 規格價(jià)格 |
100ul/2980元
購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 產(chǎn)品類(lèi)型 |
磷酸化抗體 |
| 研究領(lǐng)域 |
細胞生物 免疫學(xué) 信號轉導 泛素 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類(lèi)型 |
Polyclonal |
| 交叉反應 |
(predicted: Human, Mouse, Rat, Chicken, )
|
| 產(chǎn)品應用 |
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
215kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthesised phosphopeptide derived from human APC1 around the phosphorylation site of Ser688 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subunit:
The APC/C is composed of at least 12 subunits.
Post-translational modifications:
Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.
Similarity:
Belongs to the APC1 family.
Contains 4 PC repeats.
Database links:
Entrez Gene: 64682 Human
Entrez Gene: 535565 Cow
Entrez Gene: 475750 Dog
Entrez Gene: 17222 Mouse
Omim: 608473 Human
SwissProt: E1BAB6 Cow
SwissProt: E2RLM2 Dog
SwissProt: Q9H1A4 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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