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    Rabbit Anti-MAP4/PE-Cy7 Conjugated antibody (bs-4128R-PE-Cy7)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-4128R-PE-Cy7
    英文名稱(chēng) Rabbit Anti-MAP4/PE-Cy7 Conjugated antibody
    中文名稱(chēng) PE-Cy7標記的微管相關(guān)蛋白4抗體
    別    名 DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  信號轉導  細胞周期蛋白  細胞骨架  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 121kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human MAP4
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.

    Function:
    Non-neuronal microtubule-associated protein. Promotes microtubule assembly.

    Subunit:
    Interacts with SEPT2; this interaction impedes tubulin-binding.

    Subcellular Location:
    Cytoplasm, cytoskeleton.

    Post-translational modifications:
    Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338.

    Similarity:
    Contains 4 Tau/MAP repeats.

    Database links:

    Entrez Gene: 4134 Human

    Entrez Gene: 17758 Mouse

    Entrez Gene: 367171 Rat

    Omim: 157132 Human

    SwissProt: P27816 Human

    SwissProt: P27546 Mouse

    SwissProt: Q5M7W5 Rat

    Unigene: 517949 Human

    Unigene: 217318 Mouse

    Unigene: 443428 Mouse

    Unigene: 484451 Mouse

    Unigene: 203122 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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