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    Rabbit Anti-PIBF/FITC Conjugated antibody (bs-0420R-FITC)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-0420R-FITC
    英文名稱(chēng) Rabbit Anti-PIBF/FITC Conjugated antibody
    中文名稱(chēng) FITC標記的孕激素誘導阻斷因子抗體
    別    名 progesterone induced blocking factor; KIAA1008; PIBF 1; PIBF; PIBF1; Progesterone immunomodulatory binding factor 1; Progesterone induced blocking factor 1; PIBF1_HUMAN; RP11 505F3.1; CEP90; C13orf24; RP11-505F3.1.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 免疫學(xué)  細胞周期蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse, Rat,  (predicted: Human, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 83kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PIBF
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    C13orf24 is also known as Progesterone-induced-blocking factor 1 (PIBF1). PIBF1 is synthesized by lymphocytes of healthy pregnant women in the presence of progesterone and inhibits arachidonic acid release, by acting on the phospholipase A2 enzyme, inducing a Th2 biased immune response. It also controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect.

    Function:
    Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.

    Tissue Specificity:
    Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon.

    Database links:

    Entrez Gene: 10464 Human

    Entrez Gene: 52023 Mouse

    Entrez Gene: 306104 Rat

    Omim: 607532 Human

    SwissProt: Q8WXW3 Human

    Unigene: 441926 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    孕激素誘導阻斷因子又稱(chēng)孕酮誘導的封閉因子性蛋白。
    妊娠期間淋巴細胞生成孕酮受體且釋放一種稱(chēng)之為孕酮誘導的封閉因子性蛋白(PIBF),PIBF有很強的抗NK細胞活性,PIBF陽(yáng)性淋巴細胞分泌IL-10。
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