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    Rabbit Anti-Iroquois homeobox protein 3/BF594 Conjugated antibody (bs-7867R-BF594)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-7867R-BF594
    英文名稱(chēng) Rabbit Anti-Iroquois homeobox protein 3/BF594 Conjugated antibody
    中文名稱(chēng) BF594標記的Irx3蛋白抗體
    別    名 IRXB1; Homeodomain protein IRXB1; Iroquois homeobox protein 3; Iroquois-class homeodomain protein IRX-3; IRX 1; Irx3; IRX3_HUMAN; AI894186.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  細胞周期蛋白  細胞分化  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 52kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.

    Function:
    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

    Subunit:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    Database links:
    UniProtKB/Swiss-Prot: P78415.3

    Entrez Gene: 79191 Human

    Entrez Gene: 16373 Mouse

    Omim: 612985 Human

    SwissProt: P78415 Human

    SwissProt: P81067 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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