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    Rabbit Anti-Lysozyme/BF555 Conjugated antibody (bs-0816R-BF555)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-0816R-BF555
    英文名稱(chēng) Rabbit Anti-Lysozyme/BF555 Conjugated antibody
    中文名稱(chēng) BF555標記的溶菌酶抗體
    別    名 1 4 beta n acetylmuramidase c; 14 beta N acetylmuramidase; 14 beta N acetylmuramidase C; EC 3.2.1.17; lysosyme; Lysozyme C; Lysozyme C precursor; Lyz; LZM; Muramidase.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  激酶和磷酸酶  合成與降解  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, Monkey, Cat, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 17kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 Full length native Lysozyme
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears.

    Subcellular Location:
    Secreted.

    DISEASE:
    Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.

    Similarity:
    Belongs to the glycosyl hydrolase 22 family.

    Database links:

    Entrez Gene: 4069 Human

    Entrez Gene: 17105 Mouse

    Entrez Gene: 17110 Mouse

    Omim: 153450 Human

    SwissProt: P61626 Human

    SwissProt: P08905 Mouse

    Unigene: 524579 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    溶菌酶(lysozyme )又稱(chēng)細胞壁質(zhì)酶(muramidase)或n-乙酰胞壁質(zhì)聚糖水解酶(n-acetylmuramideglycanohydralase)。
    對于哺乳動(dòng)物溶菌酶,其牛、豬、貓、兔、猴、馬、羊等動(dòng)物的乳汁中分離出溶菌酶,其化學(xué)性質(zhì)與人溶菌酶相似。
    溶菌酶作為機體非特異免疫因子之一,參與機體多種免疫反應,在機體正常防御功能和非特異免疫中,具有保持機體生理平衡的重要作用??筛纳坪驮鰪娋奘燃毎淌珊拖δ?,激活白細胞吞噬功能,并能改善細胞抑制劑所導致的白細胞減少,從而增強機體的抵抗力。
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