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    Rabbit Anti-CYP8A1/Cy5.5 Conjugated antibody (bs-3677R-Cy5.5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-3677R-Cy5.5
    英文名稱(chēng) Rabbit Anti-CYP8A1/Cy5.5 Conjugated antibody
    中文名稱(chēng) Cy5.5標記的前列環(huán)素合成酶抗體
    別    名 CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 心血管  細胞生物  免疫學(xué)  糖尿病  新陳代謝  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 55kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

    Subcellular Location:
    Endoplasmic reticulum membrane; Single-pass membrane protein.

    Tissue Specificity:
    Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.

    Similarity:
    Belongs to the cytochrome P450 family.

    Database links:

    Entrez Gene: 5740 Human

    Entrez Gene: 19223 Mouse

    Entrez Gene: 25527 Rat

    Omim: 601699 Human

    SwissProt: Q29626 Cow

    SwissProt: Q16647 Human

    SwissProt: O35074 Mouse

    SwissProt: Q62969 Rat

    Unigene: 5247 Cow

    Unigene: 302085 Human

    Unigene: 2339 Mouse

    Unigene: 73051 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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