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    Rabbit Anti-Dopamine beta Hydroxylase/APC Conjugated antibody (bs-0596R-APC)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-0596R-APC
    英文名稱(chēng) Rabbit Anti-Dopamine beta Hydroxylase/APC Conjugated antibody
    中文名稱(chēng) APC標記的多巴胺β羥化酶抗體
    別    名 DBH; DBM; Dopamine beta hydroxylase; Dopamine-Beta-Hydroxylase; Dopamine beta monooxygenase; DOPO_RAT; DOPO_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  合成與降解  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human,  (predicted: Mouse, Rat, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 70kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DBH
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family.

    Function:
    Conversion of dopamine to noradrenaline.

    Subunit:
    Homotetramer composed of two non-covalently bound disulfide-linked dimers (By similarity).

    Subcellular Location:
    Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen (By similarity).
    Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity).

    Tissue Specificity:
    Chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system.

    Similarity:
    Belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 1 DOMON domain.

    Database links:

    Entrez Gene: 280758 Cow

    Entrez Gene: 1621 Human

    Entrez Gene: 13166 Mouse

    Entrez Gene: 25699 Rat

    Omim: 223360 Human

    Omim: 609312 Human

    SwissProt: P15101 Cow

    SwissProt: P09172 Human

    SwissProt: Q64237 Mouse

    SwissProt: Q05754 Rat

    Unigene: 223858 Human

    Unigene: 591890 Human

    Unigene: 167781 Mouse

    Unigene: 87166 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Dopamine-β-Hydroxylase(DBH)—多巴胺β羥化酶??梢詫⒍喟桶忿D化成去甲腎上腺素。是腎上腺素能神經(jīng)元的標志。
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