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    Rabbit Anti-Cyclooxygenase 1/Cy5 Conjugated antibody (bs-0582R-Cy5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-0582R-Cy5
    英文名稱(chēng) Rabbit Anti-Cyclooxygenase 1/Cy5 Conjugated antibody
    中文名稱(chēng) Cy5標記的前列腺素氧化環(huán)化酶1抗體
    別    名 Cyclooxygenase-1; COX-1; COX 1; COX1; Cyclooxygenase1; Prostaglandin-endoperoxide synthase-1; prostaglandin-endoperoxide synthase 1; PTGS-1; Prostaglandin G/H synthase 1 precursor; prostaglandin G/H synthase 1 isoform 1 precursor; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; PGH1_HUMAN; PTGS1; Prostaglandin G/H synthase 1 precursor.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  信號轉導  合成與降解  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Sheep, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 63kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Cyclooxygenase 1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].

    Function:
    May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.

    Subunit:
    Homodimer.

    Subcellular Location:
    Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

    Similarity:
    Belongs to the prostaglandin G/H synthase family.
    Contains 1 EGF-like domain.

    Database links:

    Entrez Gene: 5742 Human

    Entrez Gene: 19224 Mouse

    Entrez Gene: 24693 Rat

    Omim: 176805 Human

    SwissProt: P23219 Human

    SwissProt: P22437 Mouse

    SwissProt: Q63921 Rat

    Unigene: 201978 Human

    Unigene: 275434 Mouse

    Unigene: 44404 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    合成與降解(Synthesis and Degradation)
    COX1 前列腺素氧化環(huán)化酶-是前列腺素合成的關(guān)鍵酶之一,為誘導性酶,他參與細胞對生長(cháng)因子、腫瘤促進(jìn)因子和細胞因子的反應,這些因子均能誘導COX1表達,它也參與前列腺素的合成。
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