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    Rabbit Anti-Ghrelin Receptor/HRP Conjugated antibody (bs-11529R-HRP)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-11529R-HRP
    英文名稱(chēng) Rabbit Anti-Ghrelin Receptor/HRP Conjugated antibody
    中文名稱(chēng) 辣根過(guò)氧化物酶標記的腦腸肽受體抗體
    別    名 GH releasing peptide receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHRPR; GHS-R; GHS-R1; GHSR; GHSR_HUMAN; Growth hormone secretagogue receptor 1; Growth hormone secretagogue receptor type 1; growth hormone secretatgogue receptor.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號轉導  生長(cháng)因子和激素  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-F=1:50-200 ICC=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 41kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Ghrelin Receptor (75-135aa)
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein; this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin;however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated with autosomal idiopathicshort stature.[provided by RefSeq, Apr 2010].

    Function:
    Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Pituitary and hypothalamus.

    DISEASE:
    Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    Database links:

    Entrez Gene: 2693 Human

    Entrez Gene: 208188 Mouse

    Entrez Gene: 397372 Pig

    Entrez Gene: 84022 Rat

    Omim: 601898 Human

    SwissProt: Q6ISR8 Human

    SwissProt: Q92847 Human

    SwissProt: Q99P50 Mouse

    SwissProt: Q95254 Pig

    SwissProt: O08725 Rat

    Unigene: 130212 Human

    Unigene: 194721 Mouse

    Unigene: 16107 Pig

    Unigene: 74241 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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