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    Rabbit Anti-NPTX2/Cy5.5 Conjugated antibody (bs-11017R-Cy5.5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-11017R-Cy5.5
    英文名稱(chēng) Rabbit Anti-NPTX2/Cy5.5 Conjugated antibody
    中文名稱(chēng) Cy5.5標記的神經(jīng)細胞穿透素2抗體
    別    名 apexin; NARP; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII; NPTX2; NPTX2_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  細胞粘附分子  細胞骨架  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Dog, Cow, Sheep, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 46kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NPTX2
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis.

    Function:
    Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.

    Subunit:
    Homooligomer or heterooligomer (probably pentamer) with neuronal pentraxin receptor (NPTXR).

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.

    Similarity:
    Contains 1 pentaxin domain.

    Database links:

    Entrez Gene: 4885 Human

    Entrez Gene: 53324 Mouse

    Entrez Gene: 288475 Rat

    Omim: 600750 Human

    SwissProt: P47972 Human

    SwissProt: O70340 Mouse

    SwissProt: P97738 Rat

    Unigene: 3281 Human

    Unigene: 10099 Mouse

    Unigene: 162101 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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