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    Rabbit Anti-KCNK3/PE-Cy7 Conjugated antibody (bs-6674R-PE-Cy7)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-6674R-PE-Cy7
    英文名稱(chēng) Rabbit Anti-KCNK3/PE-Cy7 Conjugated antibody
    中文名稱(chēng) PE-Cy7標記的酸敏感鉀離子通道蛋白3抗體
    別    名 cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sensitive K+ channel; Two pore potassium channel KT3.1; KCNK3; TASK; TASK1; PPH4; TASK; TASK-1; TBAK1; KCNK3_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細胞膜受體  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Cow, Rabbit, Sheep, )
    產(chǎn)品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 43kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human KCNK3
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008].

    Function:
    pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.

    Subcellular Location:
    Membrane; Multi-pass membrane protein (Potential).

    Tissue Specificity:
    Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

    Similarity:
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

    Database links:

    Entrez Gene: 3777 Human

    Entrez Gene: 16527 Mouse

    Entrez Gene: 29553 Rat

    Omim: 603220 Human

    SwissProt: O14649 Human

    SwissProt: Q53SU2 Human

    SwissProt: O35111 Mouse

    SwissProt: O54912 Rat

    Unigene: 645288 Human

    Unigene: 439936 Mouse

    Unigene: 15536 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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