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    Rabbit Anti-Oxytocin R/AP Conjugated antibody (bs-1314R-AP)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-1314R-AP
    英文名稱(chēng) Rabbit Anti-Oxytocin R/AP Conjugated antibody
    中文名稱(chēng) 堿性磷酸酶(AP)標記的催產(chǎn)素受體(縮宮素受體)抗體
    別    名 Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 神經(jīng)生物學(xué)  生長(cháng)因子和激素  細胞膜受體  內分泌病  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
    產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 43kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse oxytocin receptor
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

    Database links:

    Entrez Gene: 281371 Cow

    Entrez Gene: 5021 Human

    Entrez Gene: 18430 Mouse

    Entrez Gene: 397092 Pig

    Entrez Gene: 25342 Rat

    Omim: 167055 Human

    SwissProt: P56449 Cow

    SwissProt: P30559 Human

    SwissProt: P97926 Mouse

    SwissProt: P32306 Pig

    SwissProt: P70536 Rat

    SwissProt: Q28756 Sheep

    Unigene: 2820 Human

    Unigene: 333310 Mouse

    Unigene: 6841 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    OTR在人的子宮平滑肌細胞膜上有縮宮素受體,縮宮素引起子宮收縮的機制可能是通過(guò)激活縮宮素受體而實(shí)現的。經(jīng)研究發(fā)現,縮宮素受體在外周組織和中樞神經(jīng)系統內均有分布??s宮素與不同組織、細胞上的縮宮素受體結合,通過(guò)多種信號轉導途徑而發(fā)揮作用。
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