<strike id="fvzf9"><input id="fvzf9"><form id="fvzf9"></form></input></strike>
    <strike id="fvzf9"><blockquote id="fvzf9"></blockquote></strike>
  1. 
    
  2. <label id="fvzf9"><optgroup id="fvzf9"></optgroup></label>

    <span id="fvzf9"><input id="fvzf9"></input></span>

  3. 掃碼關(guān)注公眾號           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
      
    客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
    国产欧美日韩视频免费61794_產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
    首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
    IGFBP5 Rabbit pAb (bs-24706R)  
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢(xún)價(jià)

    產(chǎn)品編號 bs-24706R
    英文名稱(chēng) IGFBP5 Rabbit pAb
    中文名稱(chēng) 胰島素樣生長(cháng)因子結合蛋白5抗體
    別    名 IBP 5; IBP5; IGF binding protein 5; IGF BP5; Insulin Like Growth Factor Binding Protein 5; IBP5_HUMAN; Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5.  
    研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉導  生長(cháng)因子和激素  糖尿病  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human,Mouse (predicted: Rat,Pig,Sheep,Cow,Chicken,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 30 kDa
    檢測分子量
    細胞定位 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human IGFBP5: 171-270/272 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Osteosarcoma, and at lower levels in liver, kidney and brain.

    Similarity:
    Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.

    SWISS:
    P24593

    Gene ID:
    3488

    Database links:

    Entrez Gene: 3488 Human

    Entrez Gene: 16011 Mouse

    Entrez Gene: 25285 Rat

    Omim: 146734 Human

    SwissProt: P24593 Human

    SwissProt: Q07079 Mouse

    SwissProt: P24594 Rat

    Unigene: 607212 Human

    Unigene: 405761 Mouse

    Unigene: 1593 Rat



    生長(cháng)因子和激素( Growth Factor and Hormones)
    IGFBP5胰島素樣生長(cháng)因子結合蛋白5(IGFBP-5)是一種可以與胰島素樣生長(cháng)因子(IGFs)結合的分泌性蛋白,其通過(guò)IGFs調節細胞的生長(cháng)、分化、凋亡、黏附和運動(dòng),IGFBP-5與IGFs結合可以調節IGFs與IGF-I型受體間的相互作用,改變其促有絲分裂效應、凋亡抑制效應和促細胞運動(dòng)作用。
    有人認為:由于造骨細胞能表達與IGF-1受體截然不同的IGFBP-5受體,IGFBP-5本身也是一種生長(cháng)因子,能夠不依賴(lài)IGF-I獨立作用來(lái)調節骨代謝。
    產(chǎn)品圖片
    Sample: Lane 1: Kidney (Mouse) Tissue Lysate at 40 ug Lane 2: Cerebrum (Mouse) Tissue Lysate at 40 ug Lane 3: Hela (Human) Cell Lysate at 30 ug Lane 4: HepG2 (Human) Cell Lysate at 30 ug Lane 5: MCF-7 (Human) Cell Lysate at 30 ug Primary: Anti-IGFBP5 (bs-24706R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 28 kD
    版權所有 2004-2026 radiasunchina.com 北京博奧森生物技術(shù)有限公司
    通過(guò)國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號: 00124Q34771R2M/1100
    通過(guò)國際醫療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號: CQC24QY10047R0M/1100
    京ICP備05066980號-1         京公網(wǎng)安備110107000727號
    国产剧情演绎系列丝袜高跟|一级毛片av性爱黄色网站|欧美三级午夜理伦三级|国产av巨作情欲放纵|亚洲 欧美 中文 日韩aⅴ
    <strike id="fvzf9"><input id="fvzf9"><form id="fvzf9"></form></input></strike>
      <strike id="fvzf9"><blockquote id="fvzf9"></blockquote></strike>
    1. 
      
    2. <label id="fvzf9"><optgroup id="fvzf9"></optgroup></label>

      <span id="fvzf9"><input id="fvzf9"></input></span>