| 產(chǎn)品編號 | IHC0356H |
| 英文名稱(chēng) | Human Periostin Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 人成骨細胞特異性因子2即用型免疫組化試劑盒 |
| 別 名 | A630052E07Rik; AI747096; OSF-2; OSF2; PDLPOSTN; peri; PLF; PN; POSTN; Osteoblast-specific factor 2; Periostin |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain. SWISS: Q15063 Gene ID: 10631 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human stomach tissue slide using IHC0356H (Human Periostin Kit).
Immunohistochemical analysis of paraffin embedded human mammary gland tissue slide using IHC0356H (Human Periostin Kit).
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0356H (Human Periostin Kit).
Immunohistochemical analysis of paraffin embedded human lung cancer tissue slide using IHC0356H (Human Periostin Kit).
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