| 產(chǎn)品編號 | IHC0338H |
| 英文名稱(chēng) | Human SCF Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 人干細胞生長(cháng)因子即用型免疫組化試劑盒 |
| 別 名 | DCUA; DFNA69; FPH2; FPHH; KL-1; SCF; Stem Cell Factor; C kit ligand; Ckit ligand; DKFZp686F2250; KIT ligand; Kitl; KITLG; KL 1; KL1; Mast cell growth factor; MGF; SF; SHEP7; Steel factor; Stem cell factor precursor; SCF_HUMAN |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist. SWISS: P21583 Gene ID: 4254 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0338H (Human SCF Kit).
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0338H (Human SCF Kit).
Immunohistochemical analysis of paraffin embedded human prostate tumor tissue slide using IHC0338H (Human SCF Kit).
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