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    SERPINB3 Mouse mAb (bsm-43190M)  
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
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    50ul/1180.00元
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    200ul/2800.00元
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    產(chǎn)品編號 bsm-43190M
    英文名稱(chēng) SERPINB3 Mouse mAb
    中文名稱(chēng) 絲氨酸蛋白酶抑制劑B3單克隆抗體
    別    名 HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A.  
    抗體來(lái)源 Mouse
    克隆類(lèi)型 Monoclonal
    克 隆 號
    交叉反應 Human
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 46 kDa
    檢測分子量
    細胞定位 細胞漿 分泌型蛋白 
    性    狀 Liquid
    免 疫 原 Recombinant human SERPINB3 protein 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹

    Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]




    Function:
    May act as a protease inhibitor to modulate the host immune response against tumor cells.

    Subcellular Location:
    Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

    Tissue Specificity:
    Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

    Similarity:
    Belongs to the serpin family. Ov-serpin subfamily.

    SWISS:
    P29508

    Gene ID:
    6317

    Database links:

    Entrez Gene : 6317 Human

    Omim : 600517 Human

    SwissProt : P29508 Human

    Unigene : 227948 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Human Cervical Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Human Lung squamous cell carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
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