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    ADGRE1 Rabbit pAb (bs-41204R)  
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    產(chǎn)品編號 bs-41204R
    英文名稱(chēng) ADGRE1 Rabbit pAb
    中文名稱(chēng) 表皮生長(cháng)因子樣激素受體1(EMR1)抗體
    別    名 F4/80; Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.  
    研究領(lǐng)域 免疫學(xué)  生長(cháng)因子和激素  G蛋白偶聯(lián)受體  糖蛋白  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse
    產(chǎn)品應用 Flow-Cyt=1ug/Test
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 95 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 Recombinant human ADGRE1: 241-530/886 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

    Function:
    Could be involved in cell-cell interactions.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Wide expression; increased levels in peripheral blood mononuclear cells.

    Similarity:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.

    SWISS:
    Q14246

    Gene ID:
    2015

    Database links:

    Entrez Gene: 2015 Human

    Entrez Gene: 13733 Mouse

    Omim: 600493 Human

    SwissProt: Q14246 Human

    SwissProt: Q61549 Mouse

    Unigene: 2375 Human

    Unigene: 2254 Mouse



    產(chǎn)品圖片
    Blank control(black line):Raw264.7. Primary Antibody (green line): Rabbit Anti-ADGRE1 antibody (bs-41204R) Dilution:1ug/Test; Secondary Antibody(white blue line): Goat anti-rabbit IgG-AF488 Dilution: 0.5ug/Test. Isotype control(orange line): Normal Rabbit IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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