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    產(chǎn)品編號 bs-23733R
    英文名稱(chēng) Rabbit Anti-IFNB1  antibody
    中文名稱(chēng) 干擾素β抗體
    別    名 Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-Beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN; IFNB_MOUSE.  
    Specific References  (3)     |     bs-23733R has been referenced in 3 publications.
    [IF=6.107] Nan Zang. et al. cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease. ISCIENCE. 2022 Sep;:105145  WB ;  Mouse.  
    [IF=5.191] Huiqing Hu. et al. cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress. Faseb J. 2022 May;36(5):e22266  WB ;  Mouse.  
    [IF=3.871] H.Q. Hu. et al. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes. Mol Cell Endocrinol. 2020 Dec;518:110890  WB ;  Mouse.  
    研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  干擾素  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Rat (predicted: Mouse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 20kDa
    細胞定位 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse IFNB1: 22-100/184 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.

    Function:
    Has antiviral, antibacterial and anticancer activities.

    Subunit:
    Monomer.

    Subcellular Location:
    Secreted.

    Similarity:
    Belongs to the alpha/beta interferon family.

    SWISS:
    P01575

    Gene ID:
    15977

    Database links:

    Entrez Gene: 15977 Mouse

    SwissProt: P01575 Mouse



    產(chǎn)品圖片
    Sample: Lung (Rat) Lysate at 40 ug Primary: Anti-IFN-Beta (bs-23733R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20 kD Observed band size: 32 kD
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