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    CD90/Thy-1 Rabbit pAb (bs-20640R)  
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    產(chǎn)品編號 bs-20640R
    英文名稱(chēng) CD90/Thy-1 Rabbit pAb
    中文名稱(chēng) CD90抗體
    別    名 CD90/Thy1; CD7; CD90 antigen; CDw90; FLJ33325; MGC128895; T25; Theta antigen; Thy-1; Thy 1; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1 membrane glycoprotein precursor; Thy 1.2; Thy-1 T-cell antigen; Thy1 antigen; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta; THY1_RAT; THY1_HUMAN.  
    Specific References  (6)     |     bs-20640R has been referenced in 6 publications.
    [IF=8.724] Yong Tang. et al. Phosphorylation inhibition of protein-tyrosine phosphatase 1B tyrosine-152 induces bone regeneration coupled with angiogenesis for bone tissue engineering. Bioact Mater. 2021 Jul;6:2039  IF,IHC ;  Mouse.  
    [IF=7.328] Dongdong Yao. et al. Matrix stiffness regulates bone repair by modulating 12-lipoxygenase-mediated early inflammation. Mat Sci Eng C-Mater. 2021 Sep;128:112359  IF ;  Mouse.  
    [IF=7.242] Yong Tang. et al. Laminin alpha 4 promotes bone regeneration by facilitating cell adhesion and vascularization. Acta Biomater. 2021 Mar;:  IF ;  Mouse.  
    [IF=6.353] Chen Chong. et al. 3D printed collagen/silk fibroin scaffolds carrying the secretome of human umbilical mesenchymal stem cells ameliorated neurological dysfunction after spinal cord injury in rats. Regen Biomater. 2022 Feb;:  IF ;  Human.  
    [IF=5.999] Jinsheng Li. et al. Micro/nano-topography Promotes Osteogenic Differentiation of Bone Marrow Stem Cells by Regulating Periostin Expression. COLLOID SURFACE B. 2022 Jul;:112700  FC ;  Rat.  
    [IF=2.092] Yuan H et al. MicroRNA let-7c-5p promotes osteogenic differentiation of dental pulp stem cells by inhibiting lipopolysaccharide-induced inflammation via HMGA2/PI3K/Akt signal blockade. Clinical and Experimental Pharmacology and Physiology.2018 doi:10.1111/1440-1681.13059  ICF ;  Rat.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  t-淋巴細胞  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat)
    產(chǎn)品應用 Flow-Cyt=1ug/Test
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 12 kDa
    檢測分子量 25-35
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CD90: 20-100/161 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

    Function:
    May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

    Subcellular Location:
    Cell membrane; Lipid-anchor, GPI-anchor.

    Tissue Specificity:
    Abundant in lymphoid tissues.

    Post-translational modifications:
    Glycosylation is tissue specific. Sialylation of N-glycans at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus.

    Similarity:
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    P04216

    Gene ID:
    7070

    Database links:

    Entrez Gene: 7070 Human

    Entrez Gene: 21838 Mouse

    Entrez Gene: 24832 Rat

    Omim: 188230 Human

    SwissProt: P04216 Human

    SwissProt: P01831 Mouse

    SwissProt: P01830 Rat

    Unigene: 644697 Human

    Unigene: 3951 Mouse

    Unigene: 108198 Rat



    Thy1/CD90主要表達于腦和淋巴組織,包括胸腺細胞、外周血液T細胞和一些上皮內層T細胞。
    Thy-1是一種糖基磷酸酯酰醇(GPI)固定的表面糖蛋白,Thy-1在T細胞激活、神經(jīng)系統發(fā)育及其發(fā)揮功能、細胞程序性死亡等方面發(fā)揮作用。
    產(chǎn)品圖片
    Blank control:Mouse brain. Primary Antibody (green line): Rabbit Anti-CD90 antibody (bs-20640R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-AF488 Dilution: 1μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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