| 產(chǎn)品編號 | bs-18614R |
| 英文名稱(chēng) | MAFF Rabbit pAb |
| 中文名稱(chēng) | 轉錄因子MAFF抗體 |
| 別 名 | Avian musculoaponeurotic fibrosarcoma virus(v maf) AS42 oncogene, protein F; CTA 447C4.1; hMafF; MAFF; MAFF_HUMAN; OTTHUMP00000199299; Transcription factor MafF; U MAF; U-Maf; V maf avian musculoaponeurotic fibrosarcoma oncogene family, protein F; V maf musculoaponeurotic fibrosarcoma oncogene homolog F(avian); V maf musculoaponeurotic fibrosarcoma oncogene homolog F; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F. |
| 研究領(lǐng)域 | 細胞生物 轉錄調節因子 表觀(guān)遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 18 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAFF: 1-100/164 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] Function: Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response. Subcellular Location: Nucleus. Tissue Specificity: Expressed in the term myometrium and kidney. Similarity: Belongs to the bZIP family. Maf subfamily. Contains 1 bZIP domain. SWISS: Q9ULX9 Gene ID: 23764 Database links: Entrez Gene: 23764 Human Entrez Gene: 17133 Mouse Omim: 604877 Human SwissProt: Q9ULX9 Human SwissProt: O54791 Mouse Unigene: 517617 Human Unigene: 86646 Mouse |
