| 產(chǎn)品編號 | bs-18109R |
| 英文名稱(chēng) | HVCN1 Rabbit pAb |
| 中文名稱(chēng) | 氫離子電壓門(mén)控通道蛋白1抗體 |
| 別 名 | HV 1; HV1; HVCN 1; HVCN1; HVCN1_HUMAN; Hydrogen voltage gated channel 1; Hydrogen voltage-gated channel 1; Voltage gated hydrogen channel 1; Voltage sensor domain only protein; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1; VSOP. |
| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 信號轉導 淋巴細胞 b-淋巴細胞 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 32 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HVCN1: 201-273/273 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. Subcellular Location: Membrane. Tissue Specificity: Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. Similarity: Belongs to the hydrogen channel family. SWISS: Q96D96 Gene ID: 84329 Database links: Entrez Gene: 84329 Human Entrez Gene: 74096 Mouse Omim: 611227 Human SwissProt: Q96D96 Human SwissProt: Q3U2S8 Mouse Unigene: 211511 Human Unigene: 334637 Human Unigene: 28804 Mouse |
