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    mtRNA polymerase Rabbit pAb (bs-17894R)  
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    產(chǎn)品編號 bs-17894R
    英文名稱(chēng) mtRNA polymerase Rabbit pAb
    中文名稱(chēng) 線(xiàn)粒體RNA聚合酶抗體
    別    名 APOLMT; DNA-directed RNA polymerase; DNA-directed RNA polymerase mitochondrial; h-mtRPOL; mitochondrial; MTRNAP; MtRPOL; POLRMT; polymerase(RNA) mitochondrial(DNA directed); polymerase, RNA, mitochondrial; RPOM; RPOM_HUMAN.  
    研究領(lǐng)域 細胞生物  轉錄調節因子  新陳代謝  線(xiàn)粒體  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 134 kDa
    檢測分子量
    細胞定位 細胞漿 線(xiàn)粒體
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human mtRNA polymerase: 951-1050/1230 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]

    Function:
    DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.

    Subunit:
    Interacts with TFB1M and TFB2M, leading to the stimulation of transcription. Interacts with TEFM.

    Subcellular Location:
    Mitochondrion.

    Similarity:
    Belongs to the phage and mitochondrial RNA polymerase family.

    SWISS:
    O00411

    Gene ID:
    5442

    Database links:

    Entrez Gene: 485102 Dog

    Entrez Gene: 100723303 Guinea pig

    Entrez Gene: 5442 Human

    Entrez Gene: 299604 Rat

    Omim: 601778 Human

    SwissProt: O00411 Human

    Unigene: 254113 Human

    Unigene: 24623 Rat



    產(chǎn)品圖片
    Sample: Jurkat(Human) Cell Lysate at30 ug Primary: Anti-mtRNA polymerase (bs-17894R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 134 kD Observed band size: 134 kD
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