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    HIATL1 Rabbit pAb (bs-16504R)  
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    產(chǎn)品編號 bs-16504R
    英文名稱(chēng) HIATL1 Rabbit pAb
    中文名稱(chēng) HIATL1蛋白抗體
    別    名 HIAL1_HUMAN; Hiatl1; Hippocampus abundant transcript-like protein 1.  
    研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  信號轉導  轉運蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 55 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human HIATL1: 201-300/506 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 HIAT1 is a multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hipposcampus. HIATL1 (Hippocampus abundant transcript-like protein 1) is a 506 amino acid multi-pass membrane protein that also belongs to the Major facilitator superfamily. The gene encoding HIATL1 maps to human chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

    Subcellular Location:
    Membrane.

    Similarity:
    Belongs to the major facilitator superfamily.

    SWISS:
    Q5SR56

    Gene ID:
    84641

    Database links:

    Entrez Gene: 84641 Human

    SwissProt: Q5SR56 Human

    Unigene: 555996 Human



    產(chǎn)品圖片
    Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti-HIATL1 (bs-16504R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
    Tissue/cell: Mouse liver tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-HIATL1 Polyclonal Antibody, Unconjugated(bs-16504R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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