| 產(chǎn)品編號 |
bs-16223R |
| 英文名稱(chēng) |
GALNT7 Rabbit pAb
|
| 中文名稱(chēng) |
GalNAc-T7蛋白抗體 |
| 別 名 |
GalNAc T7; GalNAc-T7; GalNAcT7; GALNT 7; Galnt7; GALT7_HUMAN; N acetylgalactosaminyltransferase 7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; Polypeptide N acetylgalactosaminyltransferase 7; pp GaNTase 7; pp-GaNTase 7; Protein UDP acetylgalactosaminyltransferase 7; Protein-UDP acetylgalactosaminyltransferase 7; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7. |
| 研究領(lǐng)域 |
細胞生物 免疫學(xué) 跨膜蛋白 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類(lèi)型 |
Polyclonal
|
| 克 隆 號 |
|
| 交叉反應 |
(predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow)
|
| 產(chǎn)品應用 |
IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 |
75 kDa |
| 檢測分子量 |
|
| 細胞定位 |
細胞漿
|
| 性 狀 |
Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human GALNT7: 321-420/657 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 緩 沖 液 |
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed |
PubMed |
| 產(chǎn)品介紹 |
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]
Function:
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.
SWISS:
Q86SF2
Gene ID:
51809
Database links:
Entrez Gene: 51809 Human
Entrez Gene: 108150 Mouse
Entrez Gene: 100171466 Orangutan
Entrez Gene: 29750 Rat
Omim: 605005 Human
SwissProt: Q86SF2 Human
SwissProt: Q80VA0 Mouse
SwissProt: Q5RFJ6 Orangutan
SwissProt: Q9R0C5 Rat
Unigene: 548088 Human
Unigene: 62886 Mouse
Unigene: 207200 Rat
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