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    DNAH6 Rabbit pAb (bs-14366R)  
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    產(chǎn)品編號 bs-14366R
    英文名稱(chēng) DNAH6 Rabbit pAb
    中文名稱(chēng) 軸絲動(dòng)力蛋白6抗體
    別    名 axonemal; Axonemal beta dynein heavy chain 6; Ciliary dynein heavy chain 6; DNAH6; Dnahc6; DNHL1; DYH6_HUMAN; Dynein heavy chain 6; FLJ37357; HL-2.  
    研究領(lǐng)域 細胞生物  信號轉導  細胞骨架  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Rat (predicted: Human,Mouse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 476 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DNAH6: 251-400/4158 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH6 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]

    Function:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

    Subcellular Location:
    Cytoplasm; cytoskeleton; cilium axoneme.

    Tissue Specificity:
    Detected in brain, testis and trachea.

    Similarity:
    Belongs to the dynein heavy chain family.

    SWISS:
    Q9C0G6

    Gene ID:
    1768

    Database links:

    Entrez Gene: 1768 Human

    Omim: 603336 Human

    SwissProt: Q9C0G6 Human

    Unigene: 249972 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DNAH6) Polyclonal Antibody, Unconjugated (bs-14366R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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