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    DDX49 Rabbit pAb (bs-14330R)  
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    產(chǎn)品編號 bs-14330R
    英文名稱(chēng) DDX49 Rabbit pAb
    中文名稱(chēng) ATP依賴(lài)RNA解旋酶DDX49抗體
    別    名 DEAD(Asp Glu Ala Asp) box polypeptide 49; DEAD box protein 49; DDX49_HUMAN; FLJ10432; Probable ATP dependent RNA helicase DDX49; R27090 2.  
    研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  轉錄調節因子  結合蛋白  細胞分化  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 45 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DDX49: 351-483/483 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX49 (DEAD-box protein 49) is a 483 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. One of several members of the DEAD-box protein family, DDX49 may function as a an RNA helicase that is involved in pre-mRNA splicing events.

    Function:
    The function of DDX49 has not yet been determined.

    Similarity:
    Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.

    SWISS:
    Q9Y6V7

    Gene ID:
    54555

    Database links:

    Entrez Gene: 54555 Human

    Entrez Gene: 234374 Mouse

    Entrez Gene: 290660 Rat

    SwissProt: Q9Y6V7 Human

    SwissProt: Q3UTV0 Mouse

    SwissProt: Q4FZF3 Mouse

    Unigene: 143187 Human

    Unigene: 388127 Mouse



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DDX49) Polyclonal Antibody, Unconjugated (bs-14330R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DDX49) Polyclonal Antibody, Unconjugated (bs-14330R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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