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    GPR162 Rabbit pAb (bs-15386R)  
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    產(chǎn)品編號 bs-15386R
    英文名稱(chēng) GPR162 Rabbit pAb
    中文名稱(chēng) G蛋白偶聯(lián)受體GPR162蛋白抗體
    別    名 A 2; A-2; A2; G protein coupled receptor 162; Gene rich cluster gene A protein; Gene rich cluster, A; Gene-rich cluster gene A protein; GP162; GP162_HUMAN; GPR162; GRCA; Probable G protein coupled receptor 162; Probable G-protein coupled receptor 162.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 64 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GPR162: 111-210/588 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR162 is a 588 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. Existing as two alternatively spliced isoforms, the gene encoding GPR162 maps to human chromosome 12p13.31. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

    Function:
    Orphan receptor.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein (By similarity).

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    Q16538

    Gene ID:
    27239

    Database links:

    Entrez Gene: 27239 Human

    Entrez Gene: 14788 Mouse

    SwissProt: Q16538 Human

    SwissProt: Q3UN16 Mouse

    Unigene: 631654 Human

    Unigene: 2514 Mouse



    產(chǎn)品圖片
    Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-GPR162 (bs-15386R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kD Observed band size: 63 kD
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