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    C1RL Rabbit pAb (bs-15087R)  
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    產(chǎn)品編號 bs-15087R
    英文名稱(chēng) C1RL Rabbit pAb
    中文名稱(chēng) 補體C1RL鏈多肽抗體
    別    名 C1r like protein; C1r like serine protease analog; C1r like serine protease analog protein; C1r LP; C1r-like protein; C1r-like serine protease analog protein; C1r-LP; C1rl; C1RL_HUMAN; C1RL1; C1RLP; CLSPa; complement C1r like proteinase; Complement C1r subcomponent-like protein; Complement component 1 r subcomponent like.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  信號轉導  轉運蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 49 kDa
    檢測分子量
    細胞定位 細胞外基質(zhì) 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human C1RL: 101-200/487 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 No data available.

    Function:
    Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).

    Similarity:
    Belongs to the peptidase S1 family.
    Contains 1 CUB domain.
    Contains 1 peptidase S1 domain.

    SWISS:
    Q9NZP8

    Gene ID:
    51279

    Database links:

    Entrez Gene: 51279 Human

    Omim: 608974 Human

    SwissProt: Q9NZP8 Human

    Unigene: 631730 Human



    產(chǎn)品圖片
    Sample: Liver(Mouse) Cell Lysate at 40 ug Primary: Anti-C1RL (bs-15087R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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