| 產(chǎn)品編號 | bs-12193R |
| 英文名稱(chēng) | FOXD1 Rabbit pAb |
| 中文名稱(chēng) | 叉頭蛋白D1抗體 |
| 別 名 | Brain Factor 2; FKH L8; FKHL 8; FKHL8; Forkhead(Drosophila) like 8; Forkhead box D1; Forkhead box protein D1; Forkhead drosophila homolog like 8; Forkhead like 8; Forkhead related activator 4; Forkhead related protein FKHL8; Forkhead related transcription factor 4; Forkhead-related protein FKHL8; Forkhead-related transcription factor 4; FOX D1; FOXD 1; foxd1; FOXD1_HUMAN; FREAC 4; FREAC-4; FREAC4. |
 |
Specific References (2) | bs-12193R has been referenced in 2 publications.
[IF=5.682] Gao, Cao. et al. BMSC-Derived Exosomes Carrying lncRNA-ZFAS1 Alleviate Pulmonary Ischemia/Reperfusion Injury by UPF1-Mediated mRNA Decay of FOXD1. MOL NEUROBIOL. 2023 Jan;:1-18 WB ; Mouse.
[IF=3.399] Qi Liu. et al. Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis:. Technol Cancer Res T. 2021;(): IHC ; Human.
|
| 研究領(lǐng)域 | 細胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細胞 轉錄調節因子 細胞分化 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rabbit,Sheep,Chicken,Dog) |
| 產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human FOXD1: 131-230/465 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
FOXD1 is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NFAT and NFkB. Deficiency of FOXD1 results in multiorgan systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation. Function: Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly. Subcellular Location: Nucleus. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: Q16676 Gene ID: 2297 Database links: Entrez Gene: 2297 Human Entrez Gene: 15229 Mouse GenBank: NP_004463 Human Omim: 601091 Human SwissProt: Q16676 Human SwissProt: Q61345 Mouse Unigene: 519385 Human Unigene: 347441 Mouse |
