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    KCTD8 Rabbit pAb (bs-12087R)  
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    產(chǎn)品編號 bs-12087R
    英文名稱(chēng) KCTD8 Rabbit pAb
    中文名稱(chēng) 鉀離子通道多聚體結構域蛋白8抗體
    別    名 BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8.  
    研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉導  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 52 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

    Function:
    Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

    Subunit:
    Interacts as a tetramer with GABRB1 and GABRB2 (By similarity).

    Subcellular Location:
    Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.

    Similarity:
    Contains 1 BTB (POZ) domain.

    SWISS:
    Q6ZWB6

    Gene ID:
    386617

    Database links:

    Entrez Gene: 386617 Human

    Entrez Gene: 243043 Mouse

    SwissProt: Q6ZWB6 Human

    SwissProt: Q50H33 Mouse

    Unigene: 479644 Human

    Unigene: 234821 Mouse



    產(chǎn)品圖片
    Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Muscle tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Rat Cerebellum tissue lysates Lane 6: Rat Stomach tissue lysates Lane 7: Rat Muscle tissue lysates Primary: Anti-KCTD8 (bs-12087R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa
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