| 產(chǎn)品編號 | bs-12058R |
| 英文名稱(chēng) | 5HT6 Receptor Rabbit pAb |
| 中文名稱(chēng) | 5-羥色胺受體6抗體 |
| 別 名 | SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6. |
 |
Specific References (1) | bs-12058R has been referenced in 1 publications.
[IF=3.707] Zhang Yuxiang. et al. The 5-HT6 Receptors in the Ventrolateral Orbital Cortex Attenuate Allodynia in a Rodent Model of Neuropathic Pain. Front Neurosci-Switz. 2020 Aug;14:884 IF ; Rat.
|
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 細胞膜受體 G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Pig,Dog,Horse) |
| 產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 47 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6: 51-150/440 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in several human brain regions, most prominently in the caudate nucleus. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P50406 Gene ID: 3362 Database links: Entrez Gene: 3362 Human Entrez Gene: 15565 Mouse Omim: 601109 Human SwissProt: P50406 Human SwissProt: Q9R1C8 Mouse Unigene: 22180 Human Unigene: 291096 Mouse Unigene: 10552 Rat |
