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    Rabbit Anti-ADGRE1  antibody (bs-7058R)  
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    產(chǎn)品編號 bs-7058R
    英文名稱(chēng) Rabbit Anti-ADGRE1  antibody
    中文名稱(chēng) 表皮生長(cháng)因子樣激素受體1(EMR1)抗體
    別    名 F4/80; Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.  
    Specific References  (10)     |     bs-7058R has been referenced in 10 publications.
    [IF=9.918] Daijun Zhou. et al. An injectable miR181a-IFI6 nanoparticles promote high-quality healing of radiation-induced skin injury. MATER TODAY ADV. 2022 Aug;15:100267  FC ;  Human.  
    [IF=7.675] Tao Yang. et al. Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages. ANTIOXIDANTS-BASEL. 2022 Oct;11(10):2050  IF ;  Mouse.  
    [IF=6.93] Kwan, Karen HL, et al. ?Silver nanaoparticles alter proteoglycan expression in the promotion of tendon repair.? Nanomedicine: Nanotechnology, Biology and Medicine (2013).  IHC-P ;  Rat.  
    [IF=5.923] Liang Hu. et al. Transient Activation of Hedgehog Signaling Inhibits Cellular Senescence and Inflammation in Radiated Swine Salivary Glands through Preserving Resident Macrophages. Int J Mol Sci. 2021 Jan;22(24):13493  WB ;  Pig.  
    [IF=5.714] Ruyi Qu. et al. Glucocorticoids improve the balance of M1/M2 macrophage polarization in experimental autoimmune uveitis through the P38MAPK-MEF2C axis. INT IMMUNOPHARMACOL. 2023 Jul;120:110392  FCM ;  Rat.  
    [IF=4.396] Yosuke Asami. et al. Rat peri-implant soft tissue specifically expressed CXCL2 on titanium implant during wound healing. 2021 Nov 30  IHC ;  Rat.  
    [IF=3.36] Tsang, Yuk-Wah, et al. "Improving immunological tumor microenvironment using electro-hyperthermia followed by dendritic cell immunotherapy." BMC Cancer 15.1 (2015): 708.  IHC-P ;  Mouse.  
    [IF=2.751] Jiachen Lv. et al. Alcohol Aggravates Acute Pancreatitis by Impairing Autophagic Flux Through Activation of AMPK Signaling Pathway. 2021 Feb 08  IHC ;  Human,Rat.  
    [IF=2.435] AHMED M et al. Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting. BIOMEDICAL ENGINEERING SOCIETY.2018 Nov.  FCM ;  Mouse&Human.  
    [IF=1.632] Liu Y et al. Isolation and characterization of ovine monocyte-derived macrophages from peripheral blood.(2018)Vet Immunol Immunopathol. Nov;205:83-92.  IF ;  Sheep.  
    研究領(lǐng)域 免疫學(xué)  生長(cháng)因子和激素  G蛋白偶聯(lián)受體  糖蛋白  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 95kDa
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ADGRE1: 701-800/886 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

    Function:
    Could be involved in cell-cell interactions.

    Subunit:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Wide expression; increased levels in peripheral blood mononuclear cells.

    Similarity:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains.
    Contains 1 GPS domain.

    SWISS:
    Q14246

    Gene ID:
    2015

    Database links:

    Entrez Gene: 2015 Human

    Entrez Gene: 13733 Mouse

    Omim: 600493 Human

    SwissProt: Q14246 Human

    SwissProt: Q61549 Mouse

    Unigene: 2375 Human

    Unigene: 2254 Mouse




    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded Mouse Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Mouse Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
    Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (bs-7058R) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
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