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    Adrenodoxin Rabbit pAb (bs-11426R)  
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    產(chǎn)品編號 bs-11426R
    英文名稱(chēng) Adrenodoxin Rabbit pAb
    中文名稱(chēng) 腎上腺皮質(zhì)線(xiàn)粒體鐵氧還蛋白抗體
    別    名 Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.  
    Specific References  (1)     |     bs-11426R has been referenced in 1 publications.
    [IF=8.786] Jiateng Hu. et al. Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics. FRONT IMMUNOL. 2023; 14: 1138126  IF ;  Mouse.  
    研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學(xué)  信號轉導  生長(cháng)因子和激素  線(xiàn)粒體  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Rat (predicted: Human,Mouse,Sheep)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 13.5 kDa
    檢測分子量
    細胞定位 細胞漿 線(xiàn)粒體
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX: 51-150/184 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

    Function:
    Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

    Subcellular Location:
    Mitochondrion matrix.

    Tissue Specificity:
    Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

    Similarity:
    Belongs to the adrenodoxin/putidaredoxin family.
    Contains 1 2Fe-2S ferredoxin-type domain.

    SWISS:
    P10109

    Gene ID:
    2230

    Database links:

    Entrez Gene: 2230 Human

    Entrez Gene: 14148 Mouse

    Entrez Gene: 29189 Rat

    Omim: 103260 Human

    SwissProt: P10109 Human

    SwissProt: P46656 Mouse

    SwissProt: P24483 Rat

    Unigene: 744 Human

    Unigene: 1061 Mouse

    Unigene: 440190 Mouse

    Unigene: 6946 Rat



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Adrenodoxin) Polyclonal Antibody, Unconjugated (bs-11426R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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