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    TACI Rabbit pAb (bs-4841R)  
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    產(chǎn)品編號 bs-4841R
    英文名稱(chēng) TACI Rabbit pAb
    中文名稱(chēng) 腫瘤壞死因子受體超家族成員13B抗體
    別    名 TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B; TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  淋巴細胞  t-淋巴細胞  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 32 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TNFRSF13B/CD267/TACI : 21-120/293 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

    Subcellular Location:
    Membrane; Single-pass type III membrane protein.

    Tissue Specificity:
    Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.

    Similarity:
    Contains 2 TNFR-Cys repeats.

    SWISS:
    O14836

    Gene ID:
    23495

    Database links:

    Entrez Gene: 23495 Human

    Entrez Gene: 57916 Mouse

    Omim: 604907 Human

    SwissProt: O14836 Human

    SwissProt: Q9ET35 Mouse

    Unigene: 158341 Human

    Unigene: 265915 Mouse



    產(chǎn)品圖片
    Sample: Lane 1: Mouse Stomach tissue lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-TACI (bs-4841R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 30 kDa
    Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti- TACI (bs-4841R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kD Observed band size: 30 kD
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