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    NIPAL3 Rabbit pAb (bs-11097R)  
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    產(chǎn)品編號 bs-11097R
    英文名稱(chēng) NIPAL3 Rabbit pAb
    中文名稱(chēng) NIPA樣蛋白3抗體
    別    名 NPAL3; NPAL-3; NIPA like domain containing 3; NIPA like protein 3; RGD1563439; RP23-332E2.5; RP3-462O23.3; NPAL3_HUMAN.  
    研究領(lǐng)域 神經(jīng)生物學(xué)  細胞粘附分子  細胞膜蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 45 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NIPAL3: 1-100/406 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 NIPAL3 is a 406 amino acid multi-pass membrane protein that belongs to the NIPA family and exists as three alternatively spliced isoforms. The gene that encodes NPAL3 consists of approximately 57,229 bases and maps to human chromosome 1p36. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the NIPA family.

    SWISS:
    Q6P499

    Gene ID:
    57185

    Database links:

    Entrez Gene: 57185 Human

    Entrez Gene: 74552 Mouse

    SwissProt: Q6P499 Human

    SwissProt: Q8BGN5 Mouse

    Unigene: 523442 Human

    Unigene: 26548 Mouse



    產(chǎn)品圖片
    Sample: U937(Human) Cell Lysate at 30 ug Primary: Anti- NIPAL3 (bs-11097R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 45 kD
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