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    FBXO36 Rabbit pAb (bs-8470R)  
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    產(chǎn)品編號 bs-8470R
    英文名稱(chēng) FBXO36 Rabbit pAb
    中文名稱(chēng) F-box蛋白相關(guān)蛋白36抗體
    別    名 F box only protein 36; F box protein 36; F-box only protein 36; Fbx 36; Fbx36; FBX36_HUMAN; FBXO 36; FLJ37592; FLJ41090.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  泛素  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Sheep,Cow,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 22 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human FBXO36: 1-100/188 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-? and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

    Function:
    Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

    Subunit:
    Directly interacts with SKP1 and CUL1

    Similarity:
    Contains 1 F-box domain.

    Gene ID:
    130888

    Database links:




    產(chǎn)品圖片
    Sample: Testis (mouse) Lysate at 40 ug placenta (mouse) Lysate at 40 ug Primary: Anti- FBXO36(bs-8470R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22kD Observed band size: 16 kD
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