| 產(chǎn)品編號 | bs-3851R |
| 英文名稱(chēng) | TNFSF9 Rabbit pAb |
| 中文名稱(chēng) | 腫瘤壞死因子配體超家族成員9抗體 |
| 別 名 | Tumor necrosis factor ligand superfamily member 9; CD137L; TNLG5A; 4 1BB L; 4-1BB-L; 4 1BB ligand; 4 1BBL; CD137 ligand; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand(TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor(ligand) superfamily member 9; receptor 4-1BB ligand; tumor necrosis factor ligand 5A; TNFL9_HUMAN; |
| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 神經(jīng)生物學(xué) 細胞表面分子 t-淋巴細胞 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Human,Mouse,Rat |
| 產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 25-27 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TNFSF9: 101-200/254 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction. Function: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Subunit: Homotrimer. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Expressed in brain, placenta, lung, skeletal muscle and kidney. Similarity: Belongs to the tumor necrosis factor family. SWISS: P41273 Gene ID: 8744 Database links: Entrez Gene: 8744 Human Omim: 606182 Human SwissProt: P41273 Human Unigene: 1524 Human |
| 產(chǎn)品圖片 |
Sample:
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-CD137L(bs-3851R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25-27 kD
Observed band size: 27 kD
Independently Validated Antibody, image provided by Science Direct, badge number 029578:Formalin-fixed and paraffin embedded human liver labeled with Anti-TNFSF9/CD137L Polyclonal Antibody, Unconjugated (bs-3851R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
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