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    GPR15 Rabbit pAb (bs-3699R)  
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    產(chǎn)品編號 bs-3699R
    英文名稱(chēng) GPR15 Rabbit pAb
    中文名稱(chēng) G蛋白偶聯(lián)受體15抗體
    別    名 GPCR GPR15; BOB; G protein coupled receptor 15; G protein coupled receptor GPR15; GPR15_HUMAN; G-protein coupled receptor 15; Brother of Bonzo.  
    研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  信號轉導  G蛋白偶聯(lián)受體  細胞表面分子  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human,Mouse,Rat (predicted: Rabbit,Dog,Horse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:200-800
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 40 kDa
    檢測分子量
    細胞定位 細胞漿 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GPR15: 51-150/360 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

    Function:
    Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    P49685

    Gene ID:
    2838

    Database links:

    Entrez Gene: 2838 Human

    Entrez Gene: 71223 Mouse

    Entrez Gene: 288181 Rat

    Omim: 601166 Human

    SwissProt: P49685 Human

    SwissProt: Q0VDU3 Mouse

    Unigene: 563128 Human

    Unigene: 359970 Mouse

    Unigene: 426544 Mouse



    G蛋白偶聯(lián)受體是一種細胞表面受體,能將細胞外的分子信號傳遞至細胞內激起細胞反應,對多種細胞行起調控作用。G蛋白偶聯(lián)受體(GPCR)參與了機體內多種生理過(guò)程的調節,是目前治療多種人類(lèi)疾病包括代謝性疾病的藥物靶點(diǎn)。
    產(chǎn)品圖片
    Tissue/cell: Mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    Tissue/cell: rat stomach tissue; Frozen section; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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