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    IL20 Rabbit pAb (bs-1834R)  
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    50ul/1180.00元
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    200ul/2800.00元
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    產(chǎn)品編號 bs-1834R
    英文名稱(chēng) IL20 Rabbit pAb
    中文名稱(chēng) 白細胞介素-20抗體
    別    名 Interleukin-20; four alpha helix cytokine; IL10D; Interleukin 20; Interleukin-20; ZCYTO10; IL20_MOUSE; Cytokine Zcyto10; IL-20; IL20_HUMAN; MGC96907; UNQ852/PRO1801.  
    研究領(lǐng)域 免疫學(xué)  糖蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Rat (predicted: Human,Mouse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 17 kDa
    檢測分子量
    細胞定位 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-20: 51-150/176 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.

    Function:
    Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed at very low levels in skin, trachea, and other tissues.

    Similarity:
    Belongs to the IL-10 family.

    Gene ID:
    58181

    Database links:

    Entrez Gene: 50604 Human

    Entrez Gene: 58181 Mouse

    SwissProt: Q9NYY1 Human

    SwissProt: Q9JKV9 Mouse



    白介素20是新發(fā)現的細胞因子,屬于白介素10家族成員。它可由活化的外周血單一核細胞和角質(zhì)形成細胞產(chǎn)生。與其他白介素10家族成員的受體亞單位有交叉反應,多用于銀屑病及風(fēng)濕病的研究。
    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (bs-1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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