| 產(chǎn)品編號 | bs-1755R |
| 英文名稱(chēng) | EGFL7 Rabbit pAb |
| 中文名稱(chēng) | 類(lèi)表皮生長(cháng)因子域7抗體 |
| 別 名 | EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGFL 7; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple epidermal growth factor like domain protein 7; NEU1 protein; NOTCH4 like protein; RP11 251M1.2; Vascular endothelial statin; VE statin; ZNEU 1; ZNEU1; EGFL7_HUMAN; EGFL7_MOUSE. |
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Specific References (1) | bs-1755R has been referenced in 1 publications.
[IF=2.24] Huang, Chunhai, et al. "VE-statin/Egfl7 expression in malignant glioma and its relevant molecular network." International Journal of Clinical Experimental Pathololgy 7.3 (2014): 1022-1031. IHC-P ; Human.
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| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 生長(cháng)因子和激素 轉錄調節因子 激酶和磷酸酶 內皮細胞 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28 kDa |
| 檢測分子量 | |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse EGFL7: 31-130/275 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro. Function: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro. Subcellular Location: Secreted (By similarity). Tissue Specificity: Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney. Similarity: Contains 2 EGF-like domains. Contains 1 EMI domain. Gene ID: 353156 Database links: Entrez Gene: 51162 Human Entrez Gene: 353156 Mouse Omim: 608582 Human SwissProt: Q9UHF1 Human Unigene: 91481 Human |
