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    CTNNAL1 Rabbit pAb (bs-1685R)  
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    產(chǎn)品編號 bs-1685R
    英文名稱(chēng) CTNNAL1 Rabbit pAb
    中文名稱(chēng) 粘附分子相關(guān)蛋白a1抗體
    別    名 ACRP; alpha catenin related protein; alpha CATU; alpha catulin; alpha2 catulin; catenin(cadherin associated protein), alpha like 1; Catenin alpha like protein 1; catenin, alpha like 1; CLLP; Highly similar to ALPHA CATENIN; CTNL1_HUMAN; alpha-catulin; alpha-catenin-related protein; Catenin alpha-like protein 1.  
    研究領(lǐng)域 免疫學(xué)  細胞膜受體  細胞粘附分子  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Rat (predicted: Human,Mouse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 81 kDa
    檢測分子量
    細胞定位 細胞漿 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CTNNAL1: 151-250/743 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms.

    Function:
    May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).

    Subunit:
    Interacts with ARHGEF1.

    Subcellular Location:
    Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.

    Tissue Specificity:
    Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.

    Similarity:
    Belongs to the vinculin/alpha-catenin family.

    SWISS:
    Q9UBT7

    Gene ID:
    8727

    Database links:

    Entrez Gene: 8727 Human

    Omim: 604785 Human

    SwissProt: Q9UBT7 Human

    Unigene: 58488 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTNNAL1) Polyclonal Antibody, Unconjugated (bs-1685R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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