| 產(chǎn)品編號 | bs-0952R |
| 英文名稱(chēng) | LHB Rabbit pAb |
| 中文名稱(chēng) | 促黃體素β亞單位抗體 |
| 別 名 | LSHB_HUMAN; Lutropin subunit beta; Lutropin beta chain; Luteinizing hormone subunit beta(LH-B; LSH-B; LH B; LSH-beta); CGB4; HH23; |
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Specific References (1) | bs-0952R has been referenced in 1 publications.
[IF=3.191] Zheng J et al. Pituitary Transcriptomic Study Reveals the Differential Regulation of lncRNAs and mRNAs Related to Prolificacy in Different FecB Genotyping Sheep. Genes (Basel). 2019 Feb 18;10(2). IF ; Sheep.
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| 研究領(lǐng)域 | 生長(cháng)因子和激素 內分泌病 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Human |
| 產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 16 kDa |
| 檢測分子量 | |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LH: 101-141/141 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008] Function: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. DISEASE: Hypogonadism LHB-related (HGON-LHB) [MIM:152780]: Characterized by infertility and pseudohermaphroditism. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the glycoprotein hormones subunit beta family. SWISS: P01229 Gene ID: 3972 Database links: Entrez Gene: 3972 Human Entrez Gene: 16866 Mouse SwissProt: P01229 Human SwissProt: O09108 Mouse LH和FSH都是垂體前葉產(chǎn)生的，由兩條多肽鏈(即а和β亞單位)經(jīng)非共價(jià)鍵結合的糖蛋白。LH和FSH都是呈脈沖式分泌，故有較明顯的日內和日間變異。 女性月經(jīng)中期的LH高峰促成排卵，男性L(fǎng)H主要刺激Legdig細胞產(chǎn)生睪丸酮，又協(xié)同FSH促進(jìn)精子成熟。與FSH同時(shí)測定，是研究和判斷下丘腦 — 垂體 — 性腺軸功能的常規檢查方法。LH的測定在預測排卵時(shí)間上具有特殊重要意義，它還可用于絕經(jīng)期檢查，不孕癥診斷和內分泌治療的監測等。 |
| 產(chǎn)品圖片 |
Sample:293T(Human) Cell Lysate at 30 ug
Primary: Anti-CD200R (bs-7351R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 16 kD
Observed band size: 19 kD
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